Ferdinand Kohle, PhD: entrepreneur, scientist, designer.
My projects sit between technology, design, and culture. Some become companies. Some become patents & research papers. Some become art. Some simply stay fun projects. Based in London.






CIPHERX TECHNOLOGIES


CEO, Founder & Inventor

CipherX is a skin-tech startup pioneering the design and manufacture of cutting-edge microneedle technology for consumer, cosmetic, and medical applications. The company’s flagship product is the world’s first painless ‘Microdot’ Tattoo.


Learn more @cipherX.tech


Awards, Features, Funders



BIOQORE TECHNOLOGIES


CSO & Founding Team

BIOQORE is an AI startup building the next generation of bioprocess intelligence. Bioqore’s AI platform Vayager learns, predicts, and optimizes cellular and biomanufacturing systems with unprecedented clarity and speed.


Learn more @bioqore.ai  





A NEEDLE WOMAN: GALAXY WAS A MEMORY, EARTH IS A SOUVENIR

 
Collaborator & Materials Designer 

A Needle Woman: Galaxy was a Memory, Earth is a Souvenir is a 14-meter-tall needle-like pavilion with a bottom diameter of 1.4 meter and iridescent appearance. Its entire façade is covered in a self-assembled nanostructure that is made from a unique, custom-made material. The pavilion was created in collaboration with the Kimsooja Studio and the Wiesner Materials Science Lab. It was first erected as part of the 2014 Cornell Council for the Arts Biennial Intimate Cosmologies: The Aesthetics of Scale in an Age of Nanotechnology, Cornell University, New York, and exhibited at Frieze Sculpture 2018, London. The installation is now part of the permanent museum collection at Yorkshire Sculpture Park in Wakefield, UK.


Learn more @Kimsooja  


Awards, Features, Funders




Cornell Dots


Developer & Co-Inventor

Cornell Dots (C Dots) are a sub-10 nm silica nanoparticle platform engineered for cancer imaging, targeting, and therapeutic delivery developed by the Wiesner Materials Science Lab. The technology became a benchmark in translational nanomedicine: protected by multiple patents, supported by high-impact publications, advanced into human clinical trials, and forming the scientific foundation for Elucida Oncology, which raised $44M to develop C Dot-based cancer therapeutics.


Learn more


Awards, Features, Funders, Partners















Publications & Patents




I have authored and co-authored peer-reviewed articles and patents in the fields of nanomedicine, materials science & design.



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2024Molecules to Masterpieces: Bridging Materials Science and the Arts.
Advanced Materials

Kohle et al

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2018Amorphous Quantum Nanomaterials
Advanced Materials

Kohle et al

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2019Inner and Outer Surface Functionalizations of Ultrasmall Fluorescent Silica Nanorings As Shown by High-Performance Liquid Chromatography
Chemistry of Materials

Kohle et al

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2019Quantitative Measure of the Size Dispersity in Ultrasmall Fluorescent Organic-Inorganic Hybrid Core-Shell Silica Nanoparticles by Small-angle X-ray Scattering
Chemistry of Materials

Barteau, Kohle et al

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2019Dye Encapsulation in Fluorescent Core-Shell Silica Nanoparticles as Probed by Fluorescence Correlation Spectroscopy
Journal of Physical Chemistry C

Kohle et al

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LIST OF PEER-REVIEWED PUBLICATIONS





2024
Advanced Materials

Kohle et al
Molecules to Masterpieces: Bridging Materials Science and the Arts.

Summary     Read More

2024
Advanced Materials

Erstling, Kohle et al
Overcoming Barriers Associated with Oral Delivery of Differently Sized Fluorescent Core-Shell Silica Nanoparticles 

Read More 

2020
Dearq

Palin, Kohle et al
BioForm – learning at the intersection of science and design

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2019
Biomater. Sci. Eng.

Kohle et al
Ultrasmall PEGylated and Targeted Core-Shell Silica Nanoparticles Carrying Methylene Blue Photosensitizer

Read More

2019
J. Phys. Chem.
Kohle et al
Dye Encapsulation in Fluorescent Core-Shell Silica Nanoparticles as Probed by Fluorescence Correlation Spectroscopy

Read More

2019
Chem. Mater.

Turker, Kohle et al
Inner and Outer Surface Functionalizations of Ultrasmall Fluorescent Silica Nanorings As Shown by High-Performance Liquid Chromatography

Read More

2019
ACS Nano
Kohle et al
High Performance Chromatographic Characterization of Surface Chemical Heterogeneities of Fluorescent Organic-Inorganic Hybrid Core-Shell Silica Nanoparticles

Read More

2019
Chem Mater

Barteau, Kohle et al
Quantitative Measure of the Size Dispersity in Ultrasmall Fluorescent Organic-Inorganic Hybrid Core-Shell Silica Nanoparticles by Small-angle X-ray Scattering

Read More

2018
Advanced Materials
Kohle et al
Amorphous Quantum Nanomaterials

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2018
PhD Dissertation, Cornell University
Kohle
Characterizing and Controlling Optical Properties of Nanomaterials for Applications in Optical Super-Resolution Microscopy, Cancer Theranostics, and Arts and Architecture

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2018
Nano Letters

Kao, Kohle et al
Fluorescent Silica Nanoparticles with Well-Separated Intensity Distributions from Batch Reactions

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2017
Langmuir

Nath, Kohle et al
Dynamics of Nanoparticles in Entangled Polymer Solutions

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2011
BSc Thesis, Heidelberg University
Kohle
Analysis of higher-order coupling constants of pyrrol (in german)

Results were published in: Faraji, S., Vazdar, M., Reddy, V.S., Eckert-Maksic, M., Lischka, H., Köppel, H. “Ab Initio Quantum Dynamical Study of the Multi-State Nonadiabatic Photodissociation of Pyrrole”. J Chem Phys, 135, 154310 (2011).

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LIST OF PATENTS



2021
GB2607115B
Kohle
Method of producing a microneedle array

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2019
WO2019213458A1
Kohle
, Wiesner
Inorganic Nanophotosensitizers and Methods of Making and Using Same

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2019
WO2019213456A1

Gardinier, Kohle, Hinckley, Wiesner
Ultrasmall Nanoparticles and Methods of Making, Using and Analyzing Same

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2018
WO2018191316A1

Kohle, Hinckley, Dhawan, Wiesner
Sulfur- or Heavy Atom-Containing Nanoparticles, Methods of Making Same, and Uses Therof

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